pentobarbital will reduce the extent or outcome of paclitaxel by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Importance Unidentified.
Watch Carefully (one)pentobarbital will minimize the extent or effect of mestranol by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
pentobarbital will reduce the level or result of ketoconazole by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Slight/Importance Unfamiliar.
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pentobarbital will reduce the level or outcome of fosphenytoin by influencing hepatic enzyme CYP2C9/10 metabolism. Use Warning/Check.
C: Use with caution if Added benefits outweigh dangers. Animal scientific tests demonstrate possibility and human reports not available or neither animal nor human scientific tests finished.
pentobarbital will decrease the level or outcome of dapsone by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minimal/Significance Not known.
pentobarbital will lessen the level or impact of aripiprazole by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.
Either improves toxicity of the other by pharmacodynamic synergism. Keep away from or Use Alternate Drug. Profound sedation, respiratory despair, coma, and Dying may final result if coadministered. Reserve concomitant prescribing of those medications in clients for whom other cure alternatives are insufficient. Limit dosages and durations into the bare minimum demanded. Monitor carefully for indications of respiratory melancholy and sedation.
Decisions regarding the timing of any elective strategies necessitating anesthesia ought to get into consideration the main advantages of the process weighed against the likely hazards
pentobarbital will reduce the extent or result of estradiol vaginal by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe.
pentobarbital will lessen the extent or influence of quinine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Minimal/Significance Unknown.
Check Closely (one)pentobarbital will lessen the extent or effect of benzhydrocodone/acetaminophen by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Check Closely. Warning when discontinuing CYP3A4 inducers that are coadministered with benzhydrocodone (prodrug of hydrocodone); plasma concentrations of hydrocodone here may well enhance and may result in probably lethal respiratory melancholy.
fentanyl intranasal and pentobarbital both of those raise sedation. Stay away from or Use Alternate Drug. Limit use to clients for whom alternate treatment alternatives are inadequate